Senior Research Scientist

Duration: 12+ months

Interview: Phone

Lawrenceville, NJ



Top Skills: MATLAB, Bioinformatics background



Summary

The Immunology Quantitative Systems Pharmacology (QSP) group is searching
for a highly motivated scientist to develop and apply innovative
translational modeling & simulation approaches in the Immunology disease
area. QSP models are mathematical models that are used to integrate
knowledge and data on disease pathophysiology and drug pharmacology in a
mechanistic manner.

This enables hypothesis testing and generation in target discovery,
translational pharmacology and clinical drug development. This position is
an exciting opportunity to broadly impact critical decision making in the
progression of multi-target drug R&D in Immunology. The successful
scientist will be working on a highly stimulating and collaborative
environment with biologists, clinicians, pharmacometricians, translational
medicine scientists, and in-house QSP modelers.



Position Responsibilities:

? Drive development and application of novel QSP Immunology models to
facilitate back-translation efforts from internal late development programs.

? Function as part of team to develop and rigorously assess the
functionality, feasibility, efficiency and validity of new models.

? Conduct extensive literature review to identify suitable mechanistic
elements, interactions, rate constants and sub-modules for incorporation
into larger systems (pharmacodynamic & efficacy) models.

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